16-year-old’s, $50,000 price for an amazing discovery of the brains of people who died of suicide
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16-year-old’s, $50,000 price for an amazing discovery of the brains of people who died of suicide

Suicide, primarily driven by impulsive actions, stems from certain factors. Namely alcohol addiction, mental illnesses, chronic diseases,  abuse, family issues, feelings of loneliness, financial loss, and professional issues.

Natasha Kulviwat, who is a remarkable high school student, did a study on brain tissue to investigate indicators related to suicide. Her astonishing discovery made her achieve the prestigious Gordon E. Moore Award. This study allows us to identify the physiological perspective of suicide.

Unveiling the Role of Inflammation

Kulviwat’s study confirms the fact that individuals who died by suicide showed higher levels of inflammatory cytokines in their brains. This discovery reveals a connection between inflammation and suicide, suggesting that high inflammation could cause the breakdown of the blood-brain barrier.

The Effect on Brain Function

Researchers discovered higher levels of the protein claudin-5 in the neurons and microvessels of individuals who died by suicide. This showed a compromised blood-brain barrier, allowing harmful substances from the bloodstream to enter the brain’s functional regions, creating a potential neurotoxic risk.

A New Method for Suicide Risk Assessment

Professionals consider psychological factors as a method to assess the risk of suicide. But the identification of biomarkers could revolutionize risk assessment. Kulviwat’s research sheds light on claudin-5 as a potential indicator of suicide risk. Providing a physiological approach to identifying and preventing suicidal cases.

Advancement in Suicide Prevention and Treatment

By identifying the physiological factors related to suicide, researchers try to develop pharmaceutical treatments. In addition,Kulviwat’s discovery indicates that anti-inflammatory medications, as opposed to conventional psychiatric drugs, offer superior potential in addressing the risk of suicide.

Findings and Future Directions

Moreover, the Kulviwat study contributes to the understanding of causes and prevention methods related to suicide. Additionally, it underscores the necessity for researchers to undertake more comprehensive studies. As a result, Kulviwat has made the decision to Join the National Institute of Health, aiming to uncover additional insights into suicide.


Natasha Kulviwat’s astonishing research into brain indicators and suicide gives a new direction to the physiological facts of this complex issue.

By identifying the link between inflammation, claudin-5, and suicide risk. Her work directs the way for future studies that could reshape our understanding of suicide prevention and treatment strategies. Continued research in this field allows us to identify new approaches to combat this public health concern.

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